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Cedars Sinai Research Updates in Lymphoma 2025

Cedars Sinai Research Updates in Lymphoma 2025

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Cedars Sinai Research Updates in Lymphoma 2025

Include: 4 videos + 22 pdfs, size: 6.5 GB Target Audience: hematologists, oncologists, pathologists Information:
Date & Location Saturday, October 18, 2025, 7:30 AM – Sunday, October 19, 2025, 3:00 PM PT, Cedars-Sinai Pavilion Education Center, Los Angeles, CA
Target Audience
Specialties – Hematology, Imaging, Internal Medicine, Oncology, Pathology & Laboratory Medicine, Radiation Oncology, Radiology, Surgery
Professions – Nurse, Nurse (Advanced Practice NP CRNA CNM CNS), Other (non-physician), Physician, Physician Assistant, Researcher (non-physician), Researcher (physician)
Overview
This conference will provide a chance for Southern California lymphoma specialists and national experts to gather and discuss updates and advancements in lymphoma treatment and research. The clinical updates sessions will highlight newly approved therapies and those in the pipeline. Case based, “How I Treat” sessions will address questions of sequencing therapies and patients selection. The scientific sessions will present high impact basic science with high translational relevance, such as new biomarkers, therapeutic targets and novel cellular therapies.
Objectives
  1. Recognize the utility of molecular testing in the classification and treatment of lymphoma
  2. Identify current evidence based treatments for Hodgkin lymphoma, diffuse large B cell lymphoma, and peripheral T cell lymphoma
  3. Describe new treatments under development including bi specific antibodies and CART therapies
  4. Collaborate as an interprofessional healthcare team to evaluate the role of molecular testing in lymphoma classification, apply evidence based treatments for various lymphoma subtypes, and discuss emerging therapies such as bispecific antibodies and CAR T cell therapies to optimize patient care through shared knowledge and coordinated decision making
   Topics:

Saturday, October 18, 2025

Session 1: Hot Topics in Clinical Lymphoma – Part I
Session Chair: TBD
Frontline Therapy for Advanced Hodgkin Lymphoma: ECHELON-1, SWOG S1826, and GHSG HD21 (BrECADD) Updates 8:10AM – 8:35AM Joe Schroers-Martin, MD
Novel Approaches in First-Line DLBCL: Beyond R-CHOP POLARIX, Zilovertamab Vedotin + R-CHP Updates 8:35AM – 9:00AM Matthew G. Mei, MD
Dual Targeting CART for Lymphoma 9:00AM – 9:25AM Akil Merchant, MD
Break and Exhibits 9:25AM – 10:10AM
Session 2: Hot Topics in Clinical Lymphoma – Part II
Session Chair: Justin Darrah
T-Cell Lymphoma 10:10AM – 10:35AM Wen-Kai Weng, MD, PhD
Role of Radiation Therapy in Lymphoma 10:35AM – 11:00AM Parag Sanghvi, MD
Lightning Round
Lightning Round: Open Clinical Trials for Lymphoma in LA area (90 sec per trial) 11:00AM – 11:30AM
Lunch and Networking
Lunch and Exhibits 11:30AM – 12:15PM
Session 3: Keynote & Basic Science Insights
Session Chair: Akil Merchant, MD
KEYNOTE ADDRESS: Spatial Profiling in Lymphoma Transformers: More than Meets the Eye 12:15PM – 1:00PM Mina Xu, MD
Microenvironment in Non-Hodgkin Lymphoma 1:00PM – 1:20PM Anthony R Colombo, PhD
Hidden Opponents: The DLBCL Microenvironment 1:20PM – 1:40PM David Russler-Germain, MD, PhD
Metabolic Profiling and Modulation of the Lymphoma Microenvironment 1:40PM – 2:00PM Akil Merchant, MD
Break and Exhibits 2:00PM – 2:20PM
Session 4: Next Generation Diagnostics and Biomarkers
Session Chair: Joseph C. Lownik, MD
Lymphoma Biomarker Development: Lessons Learned from Gene Expression Profiling 2:20PM – 2:50PM Lisa M Rimsza, MD
Developing an Automated Multiplex IF for Diagnostic/Biomarker Use in Lymphoma 2:50PM – 3:10PM Joseph C. Lownik, MD
Role of ct DNA in Lymphoma 3:10PM – 3:30PM Brian Sworder, MD, PhD
Assessments and Therapies for Older Patients with Aggressive Lymphomas 3:30PM – 3:50PM Elizabeth Brem, MD
Molecular Determinants of Sensitivity to Polatuzumab-Vedotin in DLBCL 3:50PM – 4:10PM Sean R Corcoran , MD, PhD
Adjourn 4:10PM – 4:15PM
Networking Reception
Networking Reception 4:15PM – 5:30PM

Sunday, October 19, 2025

Session 1: CAR-T Cell Therapy: Managing Complex Toxicities
Session Chair: Hitomi Hosoya, MD, PhD
Mechanisms of Neurotoxicity with IEC and Bispecific Therapies 8:00AM – 8:20AM Juliane Gust, MD, PhD
IEC-HS: Diagnosis (ASTCT Criteria), Pathophysiology, and Management 8:20AM – 8:40AM Hrishikesh Srinagesh, MD
Prophylactic Strategies for CAR-T Toxicities: Role of Early Steroids, Anakinra, and Other Novel Approaches 8:40AM – 9:00AM Caspian Oliai, MD
Secondary and T-cell Malignancies after CAR T-cell Therapy 9:00AM – 9:20AM Hitomi Hosoya, MD, PhD
Break and Exhibits 9:20AM – 9:35AM
Session 2: Clinical Debate–What is the Optimal Bridging Strategy for CAR-T Therapy
Session Chair: Justin Darrah, MD
Intro: Why bridging? 9:35AM – 9:40AM Justin Darrah, MD
Role of Bispecifics as Bridging 9:40AM – 9:50AM Justin Darrah, MD
Radiation as Bridging 9:50AM – 10:00AM Parag Sanghvi, MD
Optimal Chemotherapy for Bridging 10:00AM – 10:10AM David R. Oveisi, MD
Debate and Discussion 10:10AM – 10:35AM
BREAK/EXHIBITS 10:35AM – 11:05AM
Session 3: Next Generation Cellular Therapies for Lymphoma and Beyond (Non Accredited)
Session Chair: Yvonne Chen, PhD
Novel CART for Solid Tumors 11:05AM – 11:25AM Yvonne Chen, PhD
Innovations in TIL Therapy 11:25AM – 11:50AM Giri Ramsingh , MD
Macrophage Based Therapies 11:50AM – 12:10PM Ann Liu, Other
Engineered Protein Circuits for Cancer Therapy 12:10PM – 12:30PM Michael B. Elowitz, PhD
Closing and Lunch 12:30PM – 12:35PM
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